​Novel Method for Mass Production of Recombinant Proteins Using MSG

On 30th May, 2024, researchers at the Indian Institute of Science (IISc) unveiled a novel method to mass produce recombinant proteins, including vaccine antigens and insulin, replacing hazardous methanol with mono-sodium glutamate (MSG).

  • The new expression system aims to produce proteins for biotech industries, including milk and egg proteins, baby food supplements, nutraceuticals, and therapeutic molecules.
  • An Indian patent has been granted, and a US patent has been filed for the novel expression system, with plans to collaborate with industry partners for scaling up production.
  • The conventional method involves using methanol to activate yeast cells, which poses significant safety risks due to its ....
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