2023 Nobel Prize in Psychology or Medicine

  • The Nobel Prize in Medicine or Physiology or Medicine for 2023 has been awarded to Catalin Carico and Drew Weissman for their groundbreaking work on nucleoside base modification of messenger ribonucleic acid (mRNA).
  • In human cells, genetic information encoded in DNA is transcribed into messenger RNA (mRNA), which is used as a template for protein production.
  • mRNA vaccines work by triggering the production of proteins that stimulate the formation of virus-blocking antibodies in our cells.
  • Kariko and Weissman discovered that dendritic cells recognize in vitro transcribed mRNA as foreign, activate it, and release inflammatory signals.
  • This discovery had a ....
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