Polygenic Risk Score
A Polygenic Risk Score (PRS) is a numerical value derived by combining the collective effects of hundreds to millions of genetic variants found in a person's genome. It uses several modern genomic and bioinformatics technologies to analyze genetic data and assess disease risk.
Key Technologies used in PRS
- Genome Sequencing: Reads the DNA sequence of an individual to identify genetic variants.
- Single Nucleotide Polymorphism (SNP) Analysis: Scans genetic variants (SNPs) associated with various diseases.
- Machine Learning and Bioinformatics: Uses AI and algorithms to analyze large-scale genomic data.
- Genomic Databanks: Utilizes resources like the UK Biobank and other global genomic databases.
- Statistical Modeling: Applies probabilistic ....
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