​New Technology Enhances HIV Genome Detection

Researchers have recently developed a novel technology that uses tailored fluorogenic tests to detect the HIV genome with greater accuracy, minimizing false positives in HIV diagnosis.

  • Scientists at the Jawaharlal Nehru Centre for Advanced Scientific Research (JNCASR) have created a new diagnostic platform that targets G-Quadruplex (GQ) DNA structures in the HIV genome.
  • The GQ Topology-Targeted Reliable Conformational Polymorphism (GQ-RCP) platform was designed to offer a more reliable detection of HIV, particularly by reducing false positives and improving sensitivity.
  • GQ structures are unique four-stranded DNA formations that can be targeted for precise detection, offering a solution to the issues of cross-reactivity and low ....
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