IARC Classifies Three Common Medicines as Group 1 Carcinogens

Recently, the International Agency for Research on Cancer (IARC), the cancer research agency of the WHO, has classified hydrochlorothiazide, voriconazole and tacrolimus as “carcinogenic to humans” (Group 1).

  • Hydrochlorothiazide is used to treat high blood pressure and has been linked to squamous cell skin carcinoma and lip cancer, partly due to increased sensitivity to UV radiation.
  • Voriconazole, an antifungal medicine, has been associated with squamous cell skin carcinoma, particularly among transplant recipients receiving prolonged treatment.
  • Tacrolimus, an immunosuppressant used to prevent organ transplant rejection, has been linked to non-Hodgkin lymphoma and post-transplant lymphoproliferative disorder.
  • All three medicines are included in the WHO Model List ....
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