Key Cellular Mechanism in Huntington Disease Discovered
A team of scientists from National Centre for Cell Science (NCCS), Pune, and Savitribai Phule Pune University (SPPU) has discovered a key cellular mechanism in Huntington disease (HD) - a progressive genetic disorder which affects the brain.
HTT Gene and the Cellular Mechanism
- The scientists studied the cellular mechanism of the disease in fruit flies.
- Huntington disease is caused by a mutation in a gene called HTT. This gene is involved in the production of a protein called Huntingtin.
- Mutation in HTT gene leads to production of abnormal Huntingtin proteins which form clumps. The clumps disrupt several cellular processes and prevent ....
Do You Want to Read More?
Subscribe Now
To get access to detailed content
Already a Member? Login here