Key Cellular Mechanism in Huntington Disease Discovered

A team of scientists from National Centre for Cell Science (NCCS), Pune, and Savitribai Phule Pune University (SPPU) has discovered a key cellular mechanism in Huntington disease (HD) - a progressive genetic disorder which affects the brain.

HTT Gene and the Cellular Mechanism

  • The scientists studied the cellular mechanism of the disease in fruit flies.
  • Huntington disease is caused by a mutation in a gene called HTT. This gene is involved in the production of a protein called Huntingtin.
  • Mutation in HTT gene leads to production of abnormal Huntingtin proteins which form clumps. The clumps disrupt several cellular processes and prevent ....
Do You Want to Read More?
Subscribe Now
To get access to detailed content

Already a Member? Login here

Take Annual Subscription and get the following Advantage
The annual members of the Civil Services Chronicle can read the monthly content of the magazine as well as the Chronicle magazine archives.
Readers can study all the material since 2018 of the Civil Services Chronicle monthly issue in the form of Chronicle magazine archives.
Be an Annual Subscriber

Science & Technology