PRIYA Trial on Vitamin B12

Recently, the findings of the Pune Rural Intervention in Young Adolescents (PRIYA) trial, published recently, in the Journal of Developmental Origins of Health and Disease, indicate that vitamin B12 supplementation during adolescence improves neonatal health through epigenetic mechanisms.

  • Conducted between 2012 and 2020 within the Pune Maternal Nutrition Study (PMNS), the PRIYA trial assessed whether enhancing vitamin B12 status in adolescents could lower intergenerational metabolic risks in a population with widespread deficiency.
  • The study found that adolescent vitamin B12 supplementation significantly improved neonatal ponderal index (weight relative to height), reflecting better foetal growth and early-life nutritional outcomes.
  • These ....
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