Miniature TnpB-based Genome Editing Tool
Recently, Indian researchers created a hypercompact genome-editing system using TnpB proteins, offering a homegrown alternative to proprietary CRISPR-Cas technologies.
What is the TnpB-based Genome Editing System?
- TnpB (Transposon-associated protein) is a tiny, next-generation genome-editing enzyme that works like CRISPR but is far more compact.
- It functions as a molecular scissor, cutting plant DNA at a precise target location guided by a matching RNA sequence.
Key Features and Advantages
- Hypercompact Size: TnpB has only 400–500 amino acids, compared with 1,000–1,400 in Cas9 and ~1,300 in Cas12a.
- Easy Delivery: Its small size enables viral vector delivery directly into plant cells, eliminating the need for ....
Do You Want to Read More?
Subscribe Now
To get access to detailed content
Already a Member? Login here
Take Annual Subscription and get the following Advantage
The annual members of the Civil Services Chronicle can read the monthly content of the magazine as well as the Chronicle magazine archives.
Readers can study all the material since 2018 of the Civil Services Chronicle monthly issue in the form of Chronicle magazine archives.
Science & Technology
- 1 Ocean Thermal Energy Conversion (OTEC) Project in Lakshadweep
- 2 India Establishes Pilot Plant for Rare Earth Magnets at ARCI
- 3 NavIC Satellite IRNSS-1F Loses Atomic Clock
- 4 India Tests Indigenous Floating LiDAR Buoy System
- 5 DRDO Tests Indigenous Air Droppable Container ADC-150
- 6 INS Anjadip Commissioned
- 7 Indian Army Expands Pinaka Rocket Artillery Regiments
- 8 Minor Planet Centre Announces Discovery of 15 New Moons
- 9 ISRO Tests Upgraded CE20 Cryogenic Engine for LVM3
- 10 Scientists Detect Magnetic Waves Deep Inside the Sun
