WHO Recommends Injectable Lenacapavir for HIV Prevention

On 14th July 2025, the World Health Organization (WHO) released new guidelines recommending injectable lenacapavir (LEN) twice a year as a pre-exposure prophylaxis (PrEP) option for HIV prevention—marking a landmark policy shift unveiled at the International AIDS Society (IAS) 2025 conference in Kigali, Rwanda.

  • LEN is the first twice-yearly injectable PrEP, offering a long-acting, highly effective alternative to daily oral pills—particularly beneficial for individuals facing stigma, daily adherence issues, or limited healthcare access.
  • WHO’s recommendation comes as HIV prevention progress stalls, with 1.3 million new infections in 2024, disproportionately affecting sex workers, men who have sex with men, transgender people, people who ....
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