AI Framework Uncovers Hidden Cancer Stem Cells

On 12th August 2026, Indian researchers developed ACSCeND, an AI framework that identifies hidden cancer stem-like cells linked to tumour recurrence, metastasis and treatment resistance.

What is ACSCeND?

  • AI Framework: ACSCeND stands for AI-based Cancer Stem-like Cell Profiler and Neoplasm Deconvoluter.
  • Three Cell States: It identifies pluripotent-like, multipotent-like and unipotent-like cancer stem-cell states.
  • Bulk RNA Analysis: It uses insights from single-cell sequencing and deep learning to analyse bulk tumour RNA sequencing.
  • Large-Scale Analysis: The framework was applied to more than 25,000 tumour samples from databases including TCGA and PRECOG.

Why are Cancer Stem-like Cells Important?

  • Tumour Recurrence: These rare ....
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