CLEAR Protein Imaging Platform

In May 2026, researchers at the Jawaharlal Nehru Centre for Advanced Scientific Research (JNCASR, Bengaluru) developed a new imaging technology – Cleavable Light-Erased Antibody Reporter (CLEAR) – to improve visualization and mapping of proteins in biological samples for disease research and diagnostics.

Key Points

Main Objective: The technology enables detailed mapping of multiple proteins within the same biological sample.
Scientific Challenge Solved: CLEAR overcomes limitations of conventional imaging methods in preserving spatial protein organisation.
Working Mechanism: The platform uses light-cleavable fluorescent probes that can be erased and reused with 365 nm LED light.
Research Applications: The technology may support studies in cancer biology, immunology, neuroscience, and cellular behaviour.