Scientists Create Human Embryo Model in Lab without Eggs or Sperm

• 09 Sep 2023

Recently, scientists in Israel grew a human embryo model in a laboratory setting, devoid of eggs and sperm, by using a combination of stem cells.

Key Points:

• Innovative Approach: Israeli researchers have developed one of the most comprehensive models of a 14-day-old human embryo, utilizing a mixture of stem cells and chemicals.
• Multiple Cell Types: This mixture spontaneously assembles into various cell types necessary for fetal development, including those supporting nutrients, guiding body development, and forming essential structures like the placenta and umbilical cord.
• Low Efficiency: However, only 1% of the mixture demonstrated spontaneous assembly, making the process relatively inefficient.
• Ethical Challenges: Researchers face ethical constraints when studying the early stages of embryo development, as it's challenging to access embryos post-implantation in the uterus.
• Miscarriage and Birth Defects: Investigating the initial stages is crucial, as most miscarriages and birth defects occur during this period. It can provide insights into genetic and inherited diseases.
• Improving IVF: Understanding why some embryos develop normally and others don't could enhance in vitro fertilization success rates.
• Gene Function Exploration: These models allow scientists to explore the roles of various genes in fetal development, offering valuable insights into development processes.